Composition

Each bolus contains:

Tylosin tartrate..............600 mg

Indications

Treats shipping fever, pneumonia, foot rot, calf diphtheria, metritis in beef cattle and non-lactating dairy cattle. Treats mycoplasmal swine arthritis, pasteurella pneumonia, erysipelas, acute swine dysentery in swine.

Dosage and Administration

For oral administration: 1 bolus /60kg body weight, after the symptoms of the disease vanish, the treatment should continue for 24 hours. Not more than 3 days

Contraindication

(1)It should not be used at the same time as other macrolides, lincosamines and amidonalcohols.

(2)When combined with β - lactams, it shows antagonistic effect.

(3)Horse forbidden

Pharmacology

Tylosin is thought to have the same mechanism of action as erythromycin (binds to 50S ribosome and inhibits protein synthesis) and exhibits a similar spectrum of activity. It is a bacteriostatic antibiotic. For more specific information on organisms that tylosin is usually active against, refer to the erythromycin monography just prior to this one. Cross resistance with erythromycin occurs.

Withdrawal Time

Cattle: 21 days

Sheep and goat: 14 days

Storage and Expired Time

Store in a dry place below 30°C, away from direct sunlight

2 years

Packing

4 boluses/blister/packet