Composition
Contains per ml:

Nitroxynil          340mg

Vitamin B₁₂ (Cyanocobalamin)   100 mcg

Excipient q.s    1 ml

Deseription:

*The main phamacological action of the active ingredient in this solution, nitroxinil, is fasciolicidal. The lethal action against Fasciola hepatica has been demonstrated in vitro and in vivo in laboratory animals, and in sheep and cattle. The mechanism of action is due to uncoupling of oxidative phosphorylation. lt is also active against triclabendazole-resistant F. hepatica.

*Vitamin B₁₂ is an essential vitamin for all mammals. The vitamin is necessary for the metabolism of proteins, fats and carbohydrates. Microorganisms in the rumen of cattle and sheep manufacture vitamin B₁₂. Cobalt is an essential element for the production of vitamin B₁₂. Without sufficient cobalt, vitamin B₁₂ is not produced and symptoms of vitamin B₁₂ deficiency begin to develop.

Indications
*This product is indicated for the treatment of fascioliasis (infestations of mature and immature Fasciola hepatica) in cattle and sheep. lt is also effective, at the recommended dose rate, against adult and larval infestations of Haemonchus contortus in cattle and sheep and Haemonchus placei, Oesophagostomum radiatum and Bunostomum phlebotomum in cattle.

*ln all cases of clinical signs of vitamin B₁₂ deficiency include weight loss, suppressed appetite decreased feed efficiency, anaemia, diarrhoea, rough coat, scaly ears and weepy eyes .

Administration and Dosage

For subcutaneous or oral administration.

Cattle, sheep, goats, camels

- 1 ml per 35 kg bodyweight by subcutaneous injection.

This dosage may be increased to 1.25 ml per 35 kg bodyweight in case of acute Fascioliasis (immature flukes).

- 4 ml per 10 litres of drinking water by oral administration.

Dogs

-0.30 ml per 10 kg bodyweight by subcutaneous injection.

-0.45 ml per 10 kg bodyweight by oral administration.

Side effects

Small swellings are occasionally observed at the injection site in cattle. These can be avoided by injecting the dose in two separate sites and massaging well to disperse the solution. No systemic ill effects are to be expected when animals (including pregnant cows and ewes) are treated at normal dosage.

Withdrawal Period

Meat: Cattle: 60 days

Sheep, goats: 49 days

Storage

Store in a dry, dark place between 15℃ and 25℃.

Keep medicine away from children.

Packing
50ml, 100ml, 250ml