Each ml of suspension contains 100 mg of Albendazole, solvent q.s.to 1 ml.
It is a broad spectrum anthelmintic which is extremely active against most nematode and some cestodes worms including tape worms & adult liver fluke.
Molecular Formula: C12H15N3O2S
Molecular Weight: 265.3
CAS No.: 54965-21-8
ALBENDApit 10% with it’s low solubility, limited amount of the given dose of ALBENDApit 10% is absorbed from the stomach and intestine. However, once the drug is absorbed peak plasma level can occur in 2-4 hours. The plasma level is seldom greater than 1% of the dose administered because of it’s relatively low solubility.
Albendazole is poorly absorbed from the gastrointestinal tract due to its low aqueous solubility. Albendazole concentrations are negligible or undetectable in plasma as it is rapidly converted to the sulfoxide metabolite prior to reaching the systemic circulation. The systemic anthelmintic activity has been attributed to the primary metabolite, albendazole sulfoxide. Maximal plasma concentrations of albendazole sulfxiode are typically achived 2 to 5 hours after dosing. Albendazole sulfoxide is 70% bound to plasma protines and is widely distributed throughout the body. Albendazole is rapidly converted in the liver to the primary metabolite, albendazole sulfoxide , which is further metabolized to albendazole sulfoxide is through urine to a lesser extent and maximum through bile.
A broad spectrum anthelmintic for the treatment and control of all stages of gastro intestinal nematodes, roundworms, lungworms.
Infestation with helminths susceptible to albendazole in sheep, goats and cattle.
ALBENDApit 10% is a broad spectrum anthelmintic effective in the removal and control of the following internal parasites: Adult Liver Flukes, Heads and Segments of Tapeworms (Moniezia); Adult and 4th Stage Larvae of intestinal Worm (Cooperia spp.), Hook Worm (Bunostomum spp.), Bankrupt Worm (Trichostrongylus spp.), Nodular Worm (Oesophagostomum) Adult and 4th Stage inhibited Larvae of Ostertagia, Barberpole Worm (Trichostongylus); Adult and 4th Stage Larvae of Lung Worms (Dictyocaulus).
Gastro intestinal worms, lung worms, tape worms.
Sheep & Goats: 1.5 ml per 30 kg body weight.
Cattle:7.5 ml per 100 kg body weight.
1-Do not overdose.
2-Do not treat animals during first month of pregnancy.
Albendazole is tolerated without significant adverse effects when administered at recommended dose.
Salivation, diarrhea, and rarely foaming of the muzzle may be observed in sheep, but will disappear within few hours.
Meat: 15 days before slaughter.
Milk: 5 days after the last treatment.
In a 120ml, 250ml, 500ml or 1Liter plastic bottle.
Store in a cool, dry and dark place below 30℃.
Hello, Acalculous cholecystitis is a gallbladder inflammation without gallstones. Patients can have signs of fever, jaundice, right upper quadrant mass and pain, and Murphy’s sign, which is gallbladder pain induced by your hand when you palpate the gallbladder at the same time as the patient inhale. Patients are usually very ill due to complications of gallbladder inflammation, like Gallbladder necrosis, gangrene, and perforation, that can lead to peritonitis, sepsis, and shock.The lab values can show increased amount of Alkaline phosphatase, Aminotransferases, Bilirubin and Leukocytes. The most important test to make is Ultrasonography. Ultrasonography can show that there are no gallstones or sludge; more than 3 mm gallbladder wall thickening, more than 5 cm gallbladder distension, a striated gallbladder, mucosal sloughing, a positive Murphy’s sign induced by the ultrasonography probe, pericholecystic fluid that indicates perforation that can lead to abscess formation, and “Champagne sign” with gas bubbles in gallbladder fundus. If Ultrasonography is not enough for diagnosis, then Cholescintigraphy, a so-called HIDA scan can be used. But it takes hours to perform, so it’s not recommended in critically ill patients in whom a delay in therapy could be deadly. Here we inject Technetium labeled Hepatic IminoDiacetic Acid that is taken up by liver cells and excreted into bile to the gallbladder. If this does not happen, then it’s an indication of acalculous cholecystitis. We can inject Morphine that helps the liver cells to secrete bile into the gallbladder, and thereby makes the diagnosis easier. We treat acalculous cholecystitis with antibiotics and surgery. Before giving antibiotics, we need to take a blood culture. While we wait for the blood culture results, we start a broad-spectrum antibiotic combination, like Ampicillin-Sulbactam, or Piperacillin-Tazobactam, or Ticarcillin-Clavulanate, or Ceftriaxone-Metronidazole. When we get the blood culture results we start to treat the specific microbes that infect the gallbladder, like for example Bacteroides, Escherichia coli, Enterococcus faecalis, Klebsiella, Methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas, or Proteus species. Then it’s very important to surgically operate as soon as possible. We usually start with a Cholecystostomy. But if we don’t see an improvement within 24 hours after the operation, we start Cholecystectomy immediately. Sometimes, when there is gallbladder necrosis, perforation, or emphysematous cholecystitis, we start with Cholecystectomy right from the beginning. Thank you very much for listening!
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