Contains per ml:
Colistin sulphate 1 200 000 IU.
Enrofloxacin 100 mg.
Solvents ad 1 ml.
The combination of colistin and enrofloxacin acts additive. Enrofloxacin is a synthetic, broad spectrum antimicrobial substance, belonging to the fluoroquinoline group of antibiotics. Enrofloxacin is active against Gram-negative and Gram-positive bacteria and mycoplasmas. It is well absorbed after oral administration and rapidly excreted in the bile and urine, mostly as enrofloxacin and the metabolite ciprofloxacin. Colistin is an antibiotic from the group of polymyxins with bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella spp. It is absorbed poorly after oral administration and serum concentrations are generally undetectable in target species. Orally administered colistin is eliminated almost totally in faeces.
This product is indicated for gastrointestinal, respiratory and urinary tract infections caused by colistin and enrofloxacin sensitive micro-organisms like Campylobacter, E. coli, Haemophilus, Mycoplasma, Pasteurella and Salmonella spp. in poultry and swine.
Cases of hypersensitivity to colistin and/or enrofloxacin or to any of the excipients.
Administration to animals with seriously impaired renal and/or hepatic functions.
Cases of resistance against quinolones and/or colistin.
Administration to poultry producing eggs for human consumption or in pregnant or lactating animals.
Administration of Coliflox Oral in subtherapeutic doses or for prevention.
All membes of the quinolone family of antibiotics have the ability to cause articular lesions in young animals.
Digestive alterations may appear, such as intestinal dysbiosis, accumulation of gases, mild diarrhoea or vommiting.
Side-effects for quinolones like rash and central nervous system disturbance may occur.
During a period of rapid growth, enrofloxacin may affect joint cartilage.
For oral administration with drinking water:
Poultry : 1 litre per 2000 liters of drinking water for 3-5 days.
Pigs : 1 litre per 3000 liters of drinking water for 3-5 days.
Only sufficient medicated drinking water should be prepared to cover daily requirements. Medicated drinking water should be replaced every 24 hours.
- For meat and offal: 9 days.
Keep out of reach of children.
Bottle containing 100ml, 500ml,1000 ml, 5L.
Form of product : Medicinal oral liquids
Type of product : Antibiotics (Non penicillins)
Suited for animals : Poultry,Pigs (swine)
Active ingredients : Colistin sulphate,Enrofloxacin
Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). The illness interferes with the immune system making people with AIDS much more likely to get infections, including opportunistic infections and tumors that do not affect people with working immune systems. This susceptibility gets worse as the disease continues.
HIV is transmitted in many ways, such as anal, vaginal or oral sex, blood transfusion, contaminated hypodermic needles, exchange between mother and baby during pregnancy, childbirth, and breastfeeding. It can be transmitted by any contact of a mucous membrane or the bloodstream with a bodily fluid that has the virus in it, such as the blood, semen,vaginal fluid, preseminal fluid, or breast milk from an infected person.
The virus and disease are often referred to together as HIV/AIDS. The disease is a major health problem in many parts of the world, and is considered a pandemic, a disease outbreak that is not only present over a large area but is actively spreading. In 2009, the World Health Organization (WHO) estimated that there are 33.4 million people worldwide living with HIV/AIDS, with 2.7 million new HIV infections per year and 2.0 million annual deaths due to AIDS. In 2007,UNAIDS estimated: 33.2 million people worldwide had AIDS that year; AIDS killed 2.1 million people in the course of that year, including 330,000 children, and 76% of those deaths occurred in sub-Saharan Africa. According to UNAIDS 2009 report, worldwide some 60 million people have been infected since the start of the pandemic, with some 25 million deaths, and 14 million orphaned children in southern Africa alone.
Genetic research indicates that HIV originated in west-central Africa during the late nineteenth or early twentieth century. AIDS was first recognized by the U. S. Centers for Disease Control and Prevention in 1981 and its cause, HIV, identified in the early 1980s.
Although treatments for HIV/AIDS can slow the course of the disease, there is no known cure or vaccine. Antiretroviraltreatment reduces both the deaths and new infections from HIV/AIDS, but these drugs are expensive and the medicationsare not available in all countries. Due to the difficulty in treating HIV infection, preventing infection is a key aim in controlling the AIDS pandemic, with health organizations promoting safe sex and needle-exchange programmes in attempts to slow the spread of the virus.
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