Fenbendazole Oral Suspension
Fenbendazole is a broad spectrum anthelmintic belonging to the group of benzimidazole-carbamates applied for the control of mature and developing immature forms of nematodes (gastrointestinal roundworms and lung worms) and cestodes (tapeworms).
Contains per ml.:
Fenbendazole 100 mg.
Solvents ad. 1 ml.
Prophylaxis and treatment of gastrointestinal and respiratory worm infections and cestodes in calves, cattle, goats, sheep and swine such as: Gastrointestinal roundworms: Bunostomum, Cooperia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides, Trichuris and Trichostrongylus spp.
Lung worms: Dictyocaulus viviparus.
Tapeworms: Monieza spp.
Side effects:Hypersensitivity reactions.
Dosage:For oral administration:
Goats, swine and sheep: 1.0 ml per 20 kg body weight.
Calves and cattle: 7.5 ml per 100 kg body weight.
Shake well before use.
- For meat : 14 days.
- For milk : 4 days.
Keep out of reach of children.
Bottle containing 100, 500 and 1000 ml.
FOR Dogs and Cats
A white oral suspension of fenbendazole as a ready to administer oral anthelmintic for domestic dogs, cats, puppies and kittens. 1ml contains 100mg active ingredient fenbendazole.
A broad spectrum anthelmintic for the treatment of domestic dogs and cats infected with immature and mature stages of nematodes of the gastro-intestinal and respiratory tracts.
Adult dogs and cats:
For the treatment of adult dogs and cats infected with gastro-intestinal nematodes and
Ascarid spp. (Toxocara canis, Toxocara cati and Toxascaris leonina)
Puppies and kittens:
For the treatment of puppies and kittens infected with gastro-intestinal nematodes and puppies infected with protozoa (Giardia spp.).
For the treatment of pregnant dogs to reduce prenatal infections with Toxocara canis and the transfer of T. canis and Ancylostoma caninum to the pups via the milk.
Other:Also for the treatment of dogs infected with lungworm Oslerus (Filaroides) osleri or protozoa Giardia spp. and cats infected with lungworm Aelurostrongylus abstrusus.
Also has an ovicidal effect on nematode eggs.
Dosage and administration
Routine treatment of adult cats and dogs:1ml per 1kg bodyweight as a single oral dose.(= 100mg fenbendazole/kg bodyweight).
Practical dosage recommendations:
2 to 4kg 4ml
4 to 8kg 8ml
8 to 16kg 16ml
16 to 24kg 24ml
24 to 32kg 32ml
32 to 64kg 64ml
For dogs weighing over 64kg an extra 1ml is required for each additional 1kg bodyweight.
The dose should be mixed with feed, or administered orally directly after feeding.
Treatment should be repeated when natural re-infestation with parasitic worms occurs. Routine treatment of adult animals with minimal exposure to infection is advisable 2 to 4 times per year. More frequent treatment at 6 to 8 weekly intervals is advisable for dogs in kennels.
Puppies and kittens under six months of age:
0.5ml per kg bodyweight daily for 3 consecutive days given by mouth after feeding to unweaned animals or mixed with food for weaned animals.
(= 50mg fenbendazole/kg bodyweight daily for 3 days).
Practical dosage recommendations:
Up to 1kg 0.5ml daily for 3 days
1 to 2kg 1ml daily for 3 days
2 to 4kg 2ml daily for 3 days
4 to 6kg 3ml daily for 3 days
6 to 8kg 4ml daily for 3 days
8 to 10kg 5ml daily for 3 days
For puppies weighing over 10kg, an extra 0.5ml is required daily for each additional kg bodyweight.
Puppies should be treated at 2 weeks of age, 5 weeks of age and again before leaving the breeders premises. Treatment may also be required at 8 and 12 weeks of age. Thereafter, frequency of treatment can be reduced unless the pups remain in kennels where reinfestation occurs more readily.
1ml per 4kg bodyweight daily from day 40 of pregnancy continuously to 2 days post-whelping (approximately 25 days).(= 25mg fenbendazole/kg bodyweight daily).
Practical dosage recommendations:
4kg 1ml daily for approx. 25 days
8kg 2ml daily for approx. 25 days
12kg 3 ml daily for approx. 25 days
20kg 5ml daily for approx. 25 days
40kg 10ml daily for approx. 25 days
For dogs weighing over 40kg, an extra 1ml is required for each additional 4kg bodyweight.
As treatment of pregnant dogs is 98% effective, puppies from these dogs should themselves be treated with a three day course at 2 and 5 weeks of age.
Pregnant cats can be safely treated with this product but only require a single treatment at the routine adult dose rate. Administer 1ml per 1kg bodyweight as a single dose.(= 100mg fenbendazole/kg bodyweight).
Increased dosing for specific infections:
For the treatment of clinical worm infestations in adult dogs and cats or Giardia spp. infections in dogs, administer 1ml per 2kg bodyweight daily for 3 consecutive days.(= 50mg fenbendazole/kg bodyweight daily for 3 days).
For the control of lungworm Oslerus (Filaroides) osleri in dogs administer 1ml per 2kg bodyweight daily for 7 consecutive days.(= 50mg fenbendazole/kg bodyweight daily for 7 days).A repeat course of treatment may be required in some cases.
For the control of lungworm Aelurostrongylus abstrusus in cats administer 1ml per 2kg bodyweight daily for 3 consecutive days.(= 50mg fenbendazole/kg bodyweight daily for 3 days).
Benzimidazoles have a wide safety margin and even overdose is unlikely to cause reactions.
Contra-indications, warnings, etc.
Direct contact with the skin should be kept to a minimum. Wash hands after use.Assess bodyweight as accurately as possible before calculating the dosage.
FOR ANIMAL TREATMENT ONLY. KEEP OUT OF REACH AND SIGHT OF CHILDREN.
Pharmaceutical precautions:Do not freeze. Shake container well before use.
Wear impermeable rubber gloves.
Dispose of empty packaging and any remaining product in the household refuse.
100ml multidose bottle.
Natural vs Synthetic Ascorbic Acid
Natural and synthetic L-ascorbic acid are chemically identical, and there are no known difference in their biological activity. The possibility that the bioavailability of L-ascorbic acid from natural sources might differ from that of synthetic ascorbic acid was investigated in at least two human studies, and no clinically significant differences were observed.
The following problems should be expected with increased incidence with severe depletion of ascorbate: disorders of the immune system such as secondary infections, rheumatoid arthritis and other collagen diseases, allergic reactions to drugs, foods and other substances, chronic infections such as herpes, or sequelae of acute infections such as Guillain-Barre and Reye’s syndromes, rheumatic fever, or scarlet fever, disorders of the blood coagulation mechanisms such as hemorrhage, heart attacks, strokes, hemorrhoids and other vascular thrombosis; failure to cope properly with stresses due to suppression of the adrenal functions such as phlebitis, other inflammatory disorders, asthma and other allergies; problems of disordered collagen formation such as impaired ability to heal, excessive scarring, bed sores, varicose veins, hernias, stretch marks, wrinkles, perhaps even wear of cartilage or degeneration of spinal discs; impaired function of the nervous system such as malaise, decreased pain tolerance, and cancer from suppressed immune system and carcinogens not detoxified, etc. Note: I am not saying that ascorbate depletion is the only cause of the disorders, but I am pointing out that disorders of the systems would certainly predispose to the diseases and that these systems are known to be dependent upon ascorbate for their proper function. Not only is there the theoretical probability that these types of complications associated with infections or stresses could result from ascorbate depletion, but there was a conspicuous decrease in the expected occurrence of complications in the thousands of patients treated with oral tolerance doses or intravenous doses of ascorbate. This impression of marked decrease in these problems is shared by physicians experienced with the use of ascorbate such as Klenner and KaloKerinos.
For very severe illness, the dose he used was large and the most effective route was intravenous, but the intramuscular route was satisfactory. He gave at least 350 mg per kilogram of body weight (a 70 kg man is 150 pounds; thus 70 x 350 = 24,500 mg). This amount was put in 500cc of sterile water, usually dextrose, saline or Ringer’s solution. It was diluted so that there was at least 18cc of diluent to each gram of C.
Maintenance doses are established by the patient taking bowel tolerance doses 6 times a day for at least a week. He observes if there is any unexpected benefit such as clearing of sinuses, decrease in allergies, increase in energy, etc. Should any chronic problem be benefited, then the dose is decreased to the minimum amount producing the effect. Otherwise, a dose such as 4 to 10 grams a day divided in 3-4 doses is recommended. Patients who take ascorbate in large amounts over a long period of time should probably supplement with vitamin A and multiple mineral preparation.
How to make Sodium Ascorbate
Sodium Ascorbate is a buffered form of Vitamin C that consists of 90% Ascorbic Acid bound to 10% Sodium. This is the optimal form of Vitamin C for intravenous injection. So, if you have 100 grams of ascorbic acid then you would need 10 grams of baking soda, then add distilled water–so your ratio is 9:1. When adding water this mixture will begin to fizz. Mix gently until fizzing stops. What you have left is sodium ascorbate.
-8 grams of Ascorbic Acid
-500mgs of potassium bicarb
-30 mgs of zinc
Generally, the ratios are almost 100-160:10 or thereabouts
This will allow for better uptake of the minerals and the buffered C