Contains per ml:
Amoxycillin trihydrate 150 mg.
Gentamycin base 40 mg.
Excipients ad 1 ml.
The combination of amoxycillin and gentamicin acts synergistically against a wide range of infections caused by both Gram-positive (e.g. Staphylococcus, Streptococcus and Corynebacterium spp.) and Gram-negative (e.g. E.coli, Pasteurella, Salmonella and Pseudomonas spp.) bacteria in cattle and swine. Amoxycillin inhibits mainly in Gram-positive bacteria the cross-linkage between the linear peptidoglycan polymer chains that make up a major component
of the cell wall. Gentamicin binds to the 30S subunit of the ribosome of mainly Gram-negative bacteria, thereby interrupting protein synthesis.
Cattle: gastrointestinal, respiratory and intramammary infections caused by bacteria sensitive to the combination of amoxicillin and gentamicin, such as pneumonia, diarrhoea, bacterial enteritis, mastitis, metritis and cutaneous abscesses.
Swine: respiratory and gastrointestinal infections caused by bacteria sensitive to the combination of amoxicillin and gentamicin, such as pneumonia, colibacillosis, diarrhoea, bacterial enteritis and mastitis-metritis-agalactia syndrome (MMA).
Hypersensitivity towards amoxycillin and/or gentamicin.
Administration to animals with a seriously impaired hepatic and/or renal function.
Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Concurrent administration of nephrotoxic and/or ototoxic preparations, intravenous calcium supplementation, iron supplementation and non-steroidal antiinflammatory preparations.
For intramuscular administration. The general dosage is 1 ml per 10 kg body weight per day for 3 days.
Cattle: 30 – 40 ml per animal per day for 3 days.
Calves: 10 – 15 ml per animal per day for 3 days.
Swine: 5 – 10 ml per animal per day for 3 days.
Piglets: 1 – 5 ml per animal per day for 3 days.
Shake well before use. Do not administer more than 20 ml in cattle or more than 10 ml in swine and more than 5 ml in calves per injection site to favour absorption and dispersion.
- For meat : 30 days.
- For milk : 2 days.
Vial of 100 ml.
Hello, Acalculous cholecystitis is a gallbladder inflammation without gallstones. Patients can have signs of fever, jaundice, right upper quadrant mass and pain, and Murphy’s sign, which is gallbladder pain induced by your hand when you palpate the gallbladder at the same time as the patient inhale. Patients are usually very ill due to complications of gallbladder inflammation, like Gallbladder necrosis, gangrene, and perforation, that can lead to peritonitis, sepsis, and shock.The lab values can show increased amount of Alkaline phosphatase, Aminotransferases, Bilirubin and Leukocytes. The most important test to make is Ultrasonography. Ultrasonography can show that there are no gallstones or sludge; more than 3 mm gallbladder wall thickening, more than 5 cm gallbladder distension, a striated gallbladder, mucosal sloughing, a positive Murphy’s sign induced by the ultrasonography probe, pericholecystic fluid that indicates perforation that can lead to abscess formation, and “Champagne sign” with gas bubbles in gallbladder fundus. If Ultrasonography is not enough for diagnosis, then Cholescintigraphy, a so-called HIDA scan can be used. But it takes hours to perform, so it’s not recommended in critically ill patients in whom a delay in therapy could be deadly. Here we inject Technetium labeled Hepatic IminoDiacetic Acid that is taken up by liver cells and excreted into bile to the gallbladder. If this does not happen, then it’s an indication of acalculous cholecystitis. We can inject Morphine that helps the liver cells to secrete bile into the gallbladder, and thereby makes the diagnosis easier. We treat acalculous cholecystitis with antibiotics and surgery. Before giving antibiotics, we need to take a blood culture. While we wait for the blood culture results, we start a broad-spectrum antibiotic combination, like Ampicillin-Sulbactam, or Piperacillin-Tazobactam, or Ticarcillin-Clavulanate, or Ceftriaxone-Metronidazole. When we get the blood culture results we start to treat the specific microbes that infect the gallbladder, like for example Bacteroides, Escherichia coli, Enterococcus faecalis, Klebsiella, Methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas, or Proteus species. Then it’s very important to surgically operate as soon as possible. We usually start with a Cholecystostomy. But if we don’t see an improvement within 24 hours after the operation, we start Cholecystectomy immediately. Sometimes, when there is gallbladder necrosis, perforation, or emphysematous cholecystitis, we start with Cholecystectomy right from the beginning. Thank you very much for listening!
This is me showing how I prep for my bicillin IM injecton. When I was done I would go for a walk around the block to work the medicine in to the muscle. I would sometimes rub the area as well.