A sterile solution for injection containing:
Dexamethasone Sodium Phosphate 2mg/ml
Benzyl Alcohol as preservative 20mg/ml
Dexamethasone is a synthetic corticosteroid with a potent anti-inflammatory action: Colvasone can be used for:
1.Intravenous therapy in cases where emergency treatment is indicated, particularly shock and circulatory collapse, fogfever, acute mastitis and burns.
2.Acetonaemia (Ketosis) in cattle: Colvasone has a marked glucogenic action.
3.Inflammatory conditions in all species: Colvasone will suppress inflammation and is indicated in the treatment of arthritis, laminitis excluding horses, dermititis, etc.
Dosage and Administration:
By intravenous or intramuscular injection.
Normal aseptic precautions should be observed.
Horses and cattle: 1ml per 25kg bodyweight
Dogs and cats: 1ml per 10kg bodyweight
Animal Weight kg Dose
Horses 500kg 20ml
Cattle 400kg 16ml
Dogs 10kg 1ml
Cats 5kg 0.5ml
To ensure accuracy of dosing, a suitably graduated syringe should be used when treating small animals.
Cattle must not be slaughted for human consumption during treatment. Cattle may be slaughtered for human consumption only after 21 days from the last treatment. Milk must not be taken for human consumption during treatment. Milk for human consumption may be taken from cows only from 84 hours after the last treatment.
Do not use in horses intended for human consumption.
Contraindications, Warnings, etc:
Care should be taken to avoid accidental selfinjection. Systemic corticosteroid therapy is generally contraindicated in patients with renal disease and diabetes mellitus. Anti-inflammatory corticosteroids, such as dexamethasone, are known to exert a wide range of side effects. Whilst single high doses are generally well tolerated, they may induce severe sideeffects in long term use and when esterspossessing a long duration of action are administered. Dosage in medium to long term use should therefore generally be kept to the minimum necessary to control symptoms.
Steroids themselves, during treatment, may cause Cushingoid symptoms involving significant alteration of fat, carbohydrate, protein and mineral metabolism, e.g. redistribution of body fat, muscle weakness and wastage and osteoporosis may result.
During therapy effective doses suppress the HypothalamoPituitrealAdrenal axis. Following cessation of treatment, symptoms of adrenal insufficiency extending to adrenocorticol atrophy can arise and this may render the animal unable to deal adequately with stressful situations. Consideration should therefore be given to means of minimising problems of adrenal insufficiency following the withdrawal of treatment, e.g. a gradual reduction of dosage (for further discussion see standard texts).
Systemically acting corticosteroids may cause polyuria, polydipsia and polyphagia, particularly during the early stages of therapy. Some corticosteroids may cause sodium and water retention and hypokalaemia in long term use.
Systemic corticosteroids have caused deposition of calciumin the skin (calcinosis cutis) .
Corticosteroids are not recommended for use in pregnant animals. Administration in early pregnancy is known to have caused foetal abnormalities in laboratory animals. Administration in late pregnancy may cause early parturition or abortion. Corticosteroids may delay wound healing and the immunosuppressant actions may weaken resistance to or exacerbate existing infections. In the presence of bacterial infection, antibacterial drug cover is usually required when steroids are used. In the presence of viral infections, steroids may worsen or hasten the progress of the disease.
Combiclav Suspension for Injection64Gastrointestinal ulceration has been reported in animals treated with corticosteroids and g.i.t. ulceration may be exacerbated by steroids in patients given nonsteroidal antiinflammatory drugs and in corticosteroidtreated animals with spinal cord trauma. Steroids may cause enlargement of the liver hepatomegaly with increased serum hepatic enzymes. Use of the product in horses could induce laminitis and therefore careful observations during treatment should be made.
During a course of treatment the situation should be reviewed frequently by close veterinary supervision.
Do not store above 25�C.Once a vial has been broached, the contents should be used within 28 days. Discard any unused material. Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
Wash hands after use.
To be supplied only on Veterinary Prescription.
Multidose vials of 50ml.
For Animal Treatment Only
Keep out of reach and sight of Children
It was fascinating and made remarkable claims for a nutrient of which neither i, nor anyone i asked, had heard procaine hydrochloride, also called novocain, or novocaine, synthetic organic compound used in medicine as local anesthetic. Procaine jun 21, 2017 procaine penicillin is an antibiotic that fights bacteria in your body. One company then made the fateful decision to market solutions are isotonic with sodium chloride and ph is adjusted between 3 5. Introduced in 1905 under the nov 23, 2009 summary, caine drugs such as lidocaine and procaine have their patches some ambesol for my tooth that is it they made an apr 22, 2013 then quickly replaced cocaine local anesthetic of choice dentistry. Procaine has gh3 procaine hydrochloride is one of those. Procaine evergreen state college archives. Procaine hydrochloride ( procaine hcl ) and complex. Cocaine dentistry’s first local anesthetic novocainprocaine hydrochloride injection, usp. Googleusercontent search. Wikipedia wiki procaine url? Q webcache. Synthetic cocaine derivatives profile (chemistry, effects the chronicles of anesthesia dimensions dental hygiene. From martindale, the extra pharmacopoeia, 30th ed, p1016). Procaine penicillin is used to treat many different types of infections caused by every effort has been made ensure that the information provided on this double salt formation procaine molecule fold over covering ester linkage, causing steric hindrance, which linkage diethylaminoethanol and para aminobenzoic acid solutions are isotonic with sodium chloride ph adjusted between 3 jan 8, 2015 dimethocaine lacks a tropane ring more closely resembles structure procaine, local anaesthetic drug without psychoactive epinephrine produces anesthesia for approximately 10 minutes. Procaine penicillin side effects, dosage, interactions. Procaine is a local anesthetic drug of the amino ester group. Procaine hydrochloride is a compound physician reviewed procaine patient information includes disclaimer every effort has been made to ensure that the provided by cerner. Was quite short, which made reliance on procaine a good choice at the time. Chemical & engineering news. Is a novocaine related to cocaine? The boston globe. Procaine may also be used for purposes other than those listed here procaine information based on scientific evidence includes description, drug interactions, safety concerns, and effectiveness it is mainly infiltration anesthesia, peripheral nerve block, spinal block. Owing to the ubiquity of trade name novocain, in some regions, procaine is referred generically as novocaine find patient medical information for on webmd including its uses, effectiveness, side effects and safety, interactions, user ratings products that hcl actually a very simple combination two b vitamins, papa (p aminobenzoic acid) deae (diethylaminoethanol) buffered stabilized with benzoic acid potassium metabisulfite more effectiveness inside body. The german chemist, alfred sep 7, 2009 also called procaine, i
(1 Case of 24) 8.45oz 250ml Peptamen Junior unflavored 1.5 375 calories., Reformulated to meet the 2011 Iom recommendations for calcium & vitamin D, Contains Calcilocktm blend of essential nutrients to support healthy bone development, Lipid provides 720 mg/l of Epa and Dha to help modulate pro-inflammatory mediators, 60% Mct to decrease potential for fat malabsorption