Contains per ml::
Oxytetracycline base (as dihydrate) 300 mg.
Excipients ad 1 ml.
Oxytetracycline belongs to the group of tetracyclines and acts bacteriostatically against many Gram-positive and Gram-negative bacteria like Bordetella, Actinomyces, Erysipelothrix, Pasteurella, Staphylococcus and Streptococcus spp. Certain mycoplasma, rickettsiae, protozoa and chlamydia are also sensitive to oxytetracycline. Its mode of action is based on inhibition of bacterial protein synthesis by reversibly binding to 30S ribosomal subunits of susceptible organisms. Tetracyclines are widely distributed in the body, including kidney, lung, muscle, bile, saliva and urine. Oxytetracycline is eliminated unchanged primarily via glomerular filtration. Depending on the dose administered, one injection provides a duration of activity of 3 to 6 days.
Treatment and control of a wide range of common systemic, respiratory, urinary and local infections in cattle, sheep and swine caused by, or associated with, oxytetracycline sensitive organisms such as Bordetella bronchiseptica, Actinomyces pyogenes, Erysipelothrix rhusiopathiae, Pasteurella, Staphylococcus and Streptococcus spp., and certain mycoplasma, rickettsiae, protozoa and chlamydia. Specific indications include pasteurellosis, pneumonia, atrophic rhinitis, erysipelas, joint ill, navel ill, supportive therapy in bovine mastitis, ovine keratoconjunctivitis (pink eye) and enzootic abortion in sheep.
Hypersensitivity to tetracyclines.
Administration to animals with a seriously impaired renal and/or hepatic function.
Concurrent administration of bactericidal antibiotics such as penicillins and cephalosporins.
After intramuscular administration local reactions of a transient nature, characterised by swelling and/or hardness, may occur.
Use of the product during the period of tooth and bone development, including late pregnancy, can lead to discoloration.
Overdoses may result in nephrotoxicity.
For deep intramuscular administration.
Administer Limoxin-300 LA at the standard dose of 20 mg/kg for 3 to 4 days duration of activity for the treatment and control of conditions caused by organisms sensitive to oxytetracycline. Administer at the high dose of 30 mg/kg for the treatment and control of respiratory infections in cattle, sheep and swine.
1 ml per 15 kg body weight (20 mg/kg).
1 ml per 10 kg body weight (30 mg/kg).
Do not inject more than 10 ml in cattle and swine or more than 5 ml in sheep per injection site. Piglets should not receive more than 0.2 ml (1 day old), 0.3 ml (7 days old), 0.4 ml (14 days old) or 0.5 ml (21 days old) per injection site. Piglets older than 21 days old should receive the high dose (1 ml/10 kg; 30 mg/kg).
- For meat (standard dose):
Cattle and sheep : 28 days.
Swine : 14 days.
- For meat (high dose):
Cattle : 35 days.
Sheep and swine: 28 days.
- For milk:
Cattle : 10 days.
Sheep : 8 days.
Vial of 50 and 100 ml.
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