Each 1 ml contains Tylosin Tartrate 200mg.
Treats shipping fever, pneumonia, foot rot, calf diphtheria, metritis in beef cattle and non-lactating dairy cattle. Treats mycoplasmal swine arthritis, pasteurella pneumonia, erysipelas, acute swine dysentery in swine.
Tylosin is thought to have the same mechanism of action as ery�thromycin (binds to 50S ribosome and inhibits protein synthesis) and exhibits a similar spectrum of activity. It is a bacteriostatic antibiotic. For more specific information on or�ganisms that tylosin is usually active against, refer to the erythromycin monograph just prior to this one. Cross resistance with erythromycin occurs.
Usage and administration:
Beef and non-lactating dairy cattle: Inject IM 8 mg per pound of body Weight (1 mL per 25 pounds) once daily. Treatment should be continued 24 hours after symptoms of the disease have stopped, not to exceed 5 days. Do no inject more than 10 ml per injection site.
Swine: Inject IM 4 mg per pound of body weight (1 mL per 50 pounds) twice daily. Treatment should be continued 24 hours after symptoms of the disease have stopped, not to exceed 3 days. Do not inject more than 5 mL per injection site.
Side effect and contraindication: N/A
Do not mix Tylosin Injection with other injectable solution as this may cause precipitation of the active ingredient. Do not administer to horses or other equine species. Injection of tylosin in equines has been fatal.
Discontinue use in cattle 21 days before slaughter. Discontinue use in swine 14days before slaughter.
Storage and expired time:
Put in a cool dry place away from direct sunlight. Store in a cool, dry place under 22 �C, away from direct sunlight.
administration of atropine – a muscarinic * ACH receptor agonist (blocker). The HR and contractility return to pre-ACh administration. A second dose was administered with no effect observed via naked eye. Reason is hypothesized to be saturation of M-AChR via atropine ligand from first dose.
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