Each 100 ml contains
Colistin (as sulphate) 2400000IU
Benzylic alcohol 1 ml
Colistin (or polymyxin E) is a bactericidal antibiotic with a spectrum of activity entirely limited to the gram– bacteria.The mode of action may be in relation with the permeability of the cell through an effect on the cell membranes of the susceptible bacteria.The species usually susceptible to colistin are: Pseudomonas aeruginosa, Escherichia coli, Haemophilus inﬂuenzae, Klebsiella, Aerobacter, Pasteurella, Salmonella, Shigella Colistin is very few absorbed by the intestinal mucosa. Its activity will therefore be limited to enteric infections. Absorption being very low following oral administration, the treatment with colistin will be tolerated.
Poultry, rabbits, calves, lambs: infections caused by sensitive germs.
WAY OF ADMINISTRATION AND POSOLOGIE
Oral, in drinking water
Poultry: 75 000 IU of colistin /Kg / day correponding to 0.25 ml of COLISTIN 210 M.C.I. per
litre of drinking water for 3 days.
Other species: 50 000 IU of colistin / Kg/ 12 h corresponding to 0.25 ml of COLISTIN 210
M.C.I. twice a day for 3 days. With drinking water or milking feed.
24 months, in original closed packing below 25�C.
Meat and offal: 7 days
Eggs : nil
Bottles of 250, 500 ml, 1 L, 2.5 and 5 L.
Dr. Roger Seheult of https://www.medcram.com illustrates the key differences between the various types of penicillin antibiotic medications:
0:57 – Discovery and brief history of penicillin
1:44 – Penicillinase
2:00 – Semi-synthetic penicillins (methicillin, oxacillin, nafcillin)
3:21 – Need for gram negative antibiotic coverage (E-coli, pseudomonas, etc.)
4:26 – Aminopenicillins (ampicillin, amoxicillin)
4:49 – Extended spectrum penicillin (piperacillin, ticarcillin)
5:14 – Beta-lactamase
5:42 – Beta-lactamase inhibitors (ampicillin/sulbactam and amoxicillin/clavulanic acid
6:35 – Piperacillin/tazobactam
6:54 – Ticarcillin and clavulanate
8:18 – Staph aureus and mutations against penicillin (PCN)
8:42 – MRSA – methicillin-resistant staphylococcus aureus
9:14 – Clindamycin, trimethoprim and sulfamethoxazole, quinolones, vancomycin, daptomycin, and linezolid
10:13 – A note about cross-reactivity / low platelets
10:33 – MSSA and nafcillin
Speaker: Roger Seheult, MD
Clinical and Exam Preparation Instructor
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
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Recommended Audience: Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NDBE, RN, RT, MD, DO, PA, NP school and board examinations.
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Produced by Kyle Allred PA-C
Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical educational and exam preparation purposes, and not intended to replace recommendations by your health care provider.